Stem cell therapy for retinal diseases: update
نویسندگان
چکیده
منابع مشابه
Stem-Cell Therapy for Retinal Diseases
1.1 Stem cell (SC) therapy is not a new concept. In the aftermath of the bombings of Hiroshima and Nagasaki in 1945, researchers discovered that bone marrow transplanted into irradiated mice produced hematopoiesis (Lorenz, 1951). Hematopoietic stem cells (HSCs) were first identified in 1961 and their ability to migrate and differentiate into multiple cell types was documented (Till, 1961). Dist...
متن کاملStem cell therapy for retinal diseases.
In this review, we discuss about current knowledge about stem cell (SC) therapy in the treatment of retinal degeneration. Both human embryonic stem cell and induced pluripotent stem cell has been growth in culture for a long time, and started to be explored in the treatment of blinding conditions. The Food and Drug Administration, recently, has granted clinical trials using SC retinal therapy t...
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DOI: 10.5581/1516-8484.20120054 The term evidence based medicine (EBM) was first published in 1992, with the term defined in 1996 using a definition that is still widely used today: “The conscientious, explicit and judicious use of current best evidence about individual patient care.” The practice of EBM allows the integration of available evidence from systematic research, specifically clinica...
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Retinal and optic nerve diseases are degenerative ocular pathologies which lead to irreversible visual loss. Since the advanced therapies availability, cell-based therapies offer a new all-encompassing approach. Advances in the knowledge of neuroprotection, immunomodulation and regenerative properties of mesenchymal stem cells (MSCs) have been obtained by several preclinical studies of various ...
متن کاملCell based therapies in retinal diseases
Background Degenerative retinal diseases, including age related macular degeneration, glaucoma, and hereditary retinal dystrophies are major causes of blindness. The principal defect in these diseases is cell loss which is amenable to both cell based neuroprotective and neuroregenerative therapies. To briefly review the lines of research and potential candidates for cell based therapies among ...
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ژورنال
عنوان ژورنال: Stem Cell Research & Therapy
سال: 2011
ISSN: 1757-6512
DOI: 10.1186/scrt91